Will major universities accept me if i graduated from pennfoster?

Colleges also like community service and other activities outside of school, which I opted to do instead of joining school groups. None of the schools I've applied to seemed to care. I also went to a school with many opportunities, and didn't take many of them. So I wouldn't rule it out, it's not like most of us choose our high school. You may have a hard time getting into ivy league or something, but I'm sure you can get into a college.